Preclinical studies on sheep sperm showed that:
1. ACC improves sperm motility.
2. ACC helps increase sperm count (as a result of improved motility).
Both these parameters are essential for successful intrauterine insemination (IUI).
Preclinical studies conducted on mice showed that:
1. A study that tested the influence of ACC on mouse sperm cells showed that ACC improves sperm capacitation–a process that sperm cells must undergo in order to have the ability to penetrate and fertilize an egg.
2. An in-vitro study showed that ACC helps support initial morula growth and increases the rate of morula development into blastocysts.
3. In a group of female mice who received ACC injections before mating, the conception rate and litter size were significantly higher compared to the control group.
References
1-“Solubility and bioavailability of stabilized amorphous calcium carbonate”, Meiron, O.E., Bar-David, E., Aflalo, E.D., Shechter, A, Stepensky, D., Berman, A & Sagi, A., J Bone Miner Res 26, 364-72 (2011); https://doi.org/10.1002/jbmr.196
2-“Bone loss prevention in ovariectomized rats using stable amorphous calcium carbonate”, Shaltiel, G., Bar-David, E., Waltman, E., Shechter, A. Aflalo, E.D., Stepensky, D., Berman, A., Martin, B.R., Weaver, C.M & Sagi, A., Health 5, 18-29 (2013) Health http://dx.doi.org/10.4236/health.2013.57A2003.